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Available To Book

Upper Mississippi River

Date: Sep 12-20, 2025
Starting Price: $5,545
Trip Length: 8 nights
Trip: St. Paul, Minnesota to St. Louis, Missouri (Alton, Illinois)
Cruise line: American Cruise Lines | American Serenade
Check Availability

Discover the beauty of the Upper Mississippi on this 8-night autumnal journey aboard American Cruise Lines’ American Serenade. Begin with a complimentary pre-cruise hotel stay in St. Paul, Minnesota, renowned for its dynamic arts scene and picturesque lakes. Embark in Red Wing, a city whose pioneering story lives on in its many galleries and museums, and set sail for La Crosse. Then head to Dubuque, where you can visit the Museum of Art, Iowa’s oldest cultural institution. Explore the many districts of downtown Dubuque including Cable Car Square, the Historic Millwork District, and Historic Old Main District, once a hideaway for notorious gangster Al Capone. Enjoy the serene landscape as head to Davenport before stopping in Hannibal, to visit the boyhood home of Mark Twain and famously known as the setting for many of his writings. Finally, complete your voyage near St. Louis, famous for its soaring arch.

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Features
Itinerary
Pricing
Deck Plans

Features

MISSISSIPPI RIVER LUXURY CRUISE INCLUDING:

  • INCLUDED 1-NIGHT HOTEL STAY
  • AWARD-WINNING SHORE EXCURSIONS
  • 100% OUTSIDE-FACING STATEROOMS AND ELEVATOR ACCESS TO ALL DECKS
  • EXCLUSIVE ACCESS TO SMALL PORTS
  • ALL-INCLUSIVE FINE DINING
  • COMPLIMENTARY COCKTAILS HOURS
  • GRATUITIES, PORT CHARGES, AND FEES
  • TRANSFER FROM SHIP TO AIRPORT

Itinerary

  • September 12: St. Paul, Minnesota - Hotel Stay
  • September 13: Red Wing, Minnesota - Embark
  • September 14: La Crosse, Wisconsin
  • September 15: Cruising the Mississippi River
  • September 16: Dubuque, Iowa
  • September 17: Davenport, Iowa
  • September 18: Hannibal, Missouri
  • September 19: St. Louis, Missouri (Alton, Illinois)
  • September 20: St. Louis, Missouri (Alton, Illinois) - Disembark

Air Cities

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Deck Plans

Deck Plans
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Cancellation Policy

REFUNDS AND CANCELLATIONS: If you change your plans or cancel, your rights to a refund are limited. Submit a written cancellation to cancel@gonext.com. Upon receipt of a written cancellation from you, an American Cruise Lines non-refundable cancellation administrative fee of $250.00 per person will be applied to the following table.
Cruise Cancellation Fees:
91 days or more =full refund*
90-46 days =50% per person*
45 days or less =100% per person*
Any requests for cancellation must be communicated to Go Next in writing. Applicable refunds, if any, will be made within 14 days after the cancellation. (Subject to change; refer to your brochure for current rates.)
*All cancellations will incur an American Cruise Lines non-refundable $250 per person cancellation administrative charge.

Travel Insurance

Travel Insurance is more important than ever and we recommend it for your upcoming trip. Created with Go Next travelers in mind, our Travelex travel protection plan gives you and your loved ones options when unexpected situations affect your trip. Let us help you Dream. Explore. Travel On.

For more information on benefits, rates, and details – Click Here.

Available To Book

Upper Mississippi River

Date: Sep 12-20, 2025
Starting Price: $5,545
Trip Length: 8 nights
Trip: St. Paul, Minnesota to St. Louis, Missouri (Alton, Illinois)
Cruise line: American Cruise Lines | American Serenade
Check Availability
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